Rochelle Hines’ research is aimed at understanding neurodevelopmental processes under normal and pathological conditions, which include autism spectrum disorders, schizophrenia, and developmental epilepsies. In particular, Rochelle’s studies focus on understanding the formation and stabilization of specific synapse types during development, with an emphasis on inhibitory synapses. Rochelle employs molecular genetics, biochemistry, confocal and electron microscopy, behavioral assessments and electroencephalography in mouse models to gain understanding of how inhibitory synapse function and dysfunction during development impacts brain signaling, circuitry and behavior. The ultimate goal of Rochelle’s research is to improve our understanding of neurodevelopmental disorders and to promote novel therapeutic strategies.
Rochelle earned her PhD in Neuroscience at the University of British Columbia in Vancouver, Canada (2009), followed by a postdoctoral fellowship at Tufts University School of Medicine in Boston, MA (2015).