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Christine Cremo
( University of Nevada, Reno )
- Institution:University of Nevada, Reno
- Departments: Molecular Biosciences
- Research Fields: Regulation Of Smooth Muscle Contraction, Solution Kinetics Of Myosin-actin Interactions, Single Molecule Kinetics Of Myosin-actin Interactions, Single Molecule Interactions Of Myosin Light Chain Kinase With Cytoskeletal Proteins
- Disciplines: Biological and Biomedical Sciences, Molecular Biochemistry
- Location:Washoe County
- Funding:EPSCoR - Experimental Program to Stimulate Competitive Research
Biography
Dr. Christine Cremo has worked in the field of muscle proteins since her doctoral work on the muscarinic acetylcholine receptor in the heart. After working on fluorescent nucleotide derivatives for studies on skeletal myosin structure and function, she moved on to try to understand the regulation of the smooth muscle myosin ATPase by phosphorylation of the regulatory light chain. The focus has been on structure-function relationships. This work is ongoing, as well as a new focus on structure-function relationships of smooth muscle myosin light chain kinase. This work has high relevance to several human diseases such as asthma, hypertension, and gastrointestinal disorders.