My interests focus on organic and polymer synthesis in general. More specifically, we are interested in developing novel light-emitting and liquid-crystalline polymers for their multitude applications in modern technology including biosensors. In another project, we are developing ionic liquids based on the concept of green chemistry, and liquid-crystalline and light-emitting organic salts to make them functional materials. Carbon nanotube-based composite materials based on ionic polymers are of significant interest in our group. In recent years, we are also actively pursuing for the development of cisplatin analogs for the development cancer therapy.
The brain operates as a complex orchestration that involves many different cellular players. Dr. Dustin Hines’ research is aimed at understanding the role that glial cells play under normal and pathological conditions, which include neuropsychiatric disorders (depression), traumatic brain injury, stroke and Alzheimer disease. In particular, Dr. Hines researches how astrocytes and microglia cells both talk and listen to neurons. Dr. Hines employs molecular genetics, biochemistry, confocal and two photon microscopy, electrophysiology and behavioral assessments in mouse models to gain understanding of how glia cells impact brain signaling, circuitry and behavior. Dr. Hines’ research ultimately is directed towards understanding how all of the cells of the brain are orchestrated into the precise symphony that we call behavior.
Dr. Markus Berli’s research interests focus on modeling and measurement of soil structural dynamics affecting fluid flow and solute transport. Key issues are the connection of hydraulics and mechanics of soils at the micro-scale and upscaling physical soil behavior from pore to sample- and eventually field-scale.
Further areas of interest are: New methods for in-situ characterization of soil hydraulic and mechanical properties; improved characterization of soil pore geometry using X-ray-Micro-Tomography and pore water flow employing Neutron-Tomography; improved methods to assess and predict soil deterioration due to mechanical impacts.
His vision is that micro-scale coupling of soil hydraulics and mechanics with chemical and microbial processes will provide a conceptual framework for an improved understanding of fluid flow, contaminant fate and transport in the vadose zone, to sustain soil productivity and to secure water resources of sufficient quality and quantity world-wide.
research in computationally efficient intelligent systems. The lab combines computer vision, machine learning, and pattern recognition to develop “real” solutions. Intelligent systems are those that are able to observe the world, learn from these observations, and understand the environment. The real-time systems are designed to operate continuously and robustly through all operating modes.
Research areas of interest include traffic monitoring and pedestrian safety, activity analysis and assessment, visual object recognition, self-driving cars.
Helen J. Wing is an Associate Professor of Molecular Microbiology in the School of Life Sciences at the University of Nevada, Las Vegas. She obtained her Ph.D. in Biochemistry from the University of Birmingham (UK) in 1997, where she studied transcriptional gene regulation in Escherichia coli. She worked with both Prof. Stephen J.W. Busby and Prof. John R. Guest in her first post-doctoral position, where she employed biochemical approaches to study transcription. In 2000, Helen moved to the U.S. to take a post-doctoral position with Marcia B. Goldberg M.D. at Harvard Medical School and Massachusetts General Hospital. It was here that she became interested in the transcriptional regulation of Shigella virulence genes and antimicrobial peptides. She joined the faculty at the University of Nevada, Las Vegas in 2005.
The primary focus of my research laboratory is virulence gene expression in the bacterial pathogen Shigella flexneri, the causal agent of bacillary dysentery, which is estimated to kill over 1 million people each year. All four species of Shigella harbor a large virulence plasmid, which carries most of the genes required to cause disease in the human host, including those required for invasion, type III secretion and actin-based motility, a process that allows bacteria to spread from one human cell to another. We are interested in the environmental cues, the timing and the molecular events that trigger the expression of virulence genes. We are particularly interested in the complex interplay between nucleoid structuring proteins, proteins that facilitate the packaging of DNA into tiny cells, and the transcriptional regulators of virulence in Shigella VirF and VirB.
Overview of current research projects:
Optimization Algorithms and their Applications to Mechanical Engineering Design
Finite Element Analysis of Mechanical Components and Systems
Dynamic Analysis and Control of Mechanical Systems with Emphasis on Flexible Robots
Analysis and Design of Robots and Mechanisms
Biomedical applications of mechanical design
Characterization of biomaterials
Characterization of Material Properties under Impact Loading.
Fuzzy Logic Control Applications.