Sarrah Dunham-Cheatham

I am a research scientist with a background in environmental chemistry, geochemistry, and soil science. I am especially interested in applying bench-scale experiments and molecular level characterizations to understand field-scale behavior and fate of environmental contaminants and compounds.

Nicholas Borotto

My research program strives to improve mass spectrometric-based detection and analysis of biomolecules. In particular, we pair mass spectrometry with chemical derivatization, photon irradiation, ion mobility, and radical chemistry to elucidate the three-dimensional structure of proteins, better characterize the acidic and hydrophobic proteome, detect and localize post-translational modifications. Centered at the interface of chemistry and biology, my research program provides students with the opportunity to tackle both biochemically-focused projects and biophysical questions at the core of the techniques themselves. Currently, my group is recruiting students for three projects:

1) Equipping a carbon monoxide laser to a mass spectrometer, characterizing the behavior of irradiated biomolecules, and applying infrared multiphoton dissociation (IRMPD) to instruments and at pressure regimes traditionally precluded from this technique.

2) Probing protein three-dimensional structure with photocaged small molecule reagents both in vitro and in vivo and demonstrating the utility of the temporal and spatial control that is provided by these probes.

3) Applying the tandem mass spectrometry technique free-radical initiated peptide sequencing (FRIPS) to complex mixtures of anions.

Mary Cablk

Dr. Mary E. Cablk is an Emeritus Faculty at DRI. She is an expert in detection and systems. In her research she draws upon knowledge from multiple fields such as olfaction, analytical chemistry, learning, cognitive and industrial/occupational psychology, forensics, spatial analysis, pattern analysis, and image processing. Her interests focus on transforming qualitative observation into quantitative data and combining multiple input data types to solve complex challenges related to detection, in a field setting. Her research and expertise has taken her around the world where she has addressed audiences and worked with colleagues on landmine detection, wildlife detection, recovery of human remains, and search and rescue, among others. She works closely with relevant agencies and organizations on development and implementation of credentialing and standards for canine teams in a variety of disciplines. Dr. Cablk has been instrumental in developing a Ph.D. program in forensic anthropology at the University of Nevada Reno, where she is an adjunct professor and mentors graduate students. She is an auxiliary deputy with several county Sheriff Offices in the State of Nevada and is a resource to the State of California Governor’s Office of Emergency Services.

Expert in remote sensing including olfaction and optical. Uses quantitative methods from multiple input data types to conduct scientific analyses related to detection, including spatial analyses.